Product Usage: For Research Use Only – Not for Human or Veterinary Use

This product is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is strictly intended for in vitro research by qualified professionals. Any use in humans or animals is strictly prohibited and may violate federal, state, or local laws, including the Federal Food, Drug, and Cosmetic Act. No therapeutic or diagnostic application is implied or permitted. The purchaser assumes all responsibility for compliance with applicable regulations.

Orfo Fuel 500 MCG Capsules

Orfo Fuel 500mcg Capsules. This blend combines Orforglipron, a non-peptide GLP-1 receptor agonist in clinical development, with SLU-PP-332, a small-molecule pan-ERR agonist studied preclinically as an exercise-mimetic compound. Supplied at research-grade purity for laboratory use only.

$325.00

This blend combines two small-molecule compounds studied in different but metabolically related areas of the research literature: Orforglipron, an oral, non-peptide GLP-1 receptor agonist currently in clinical development, and SLU-PP-332, a preclinical pan-ERR (estrogen-related receptor) agonist studied as an exercise-mimetic compound.

Product Details

  • What is Orforglipron?
  • What is SLU-PP-332?
  • Chemical Identity
  • Research Applications

What is Orforglipron?

Orforglipron is a synthetic, non-peptide small molecule studied as an agonist at the GLP-1 receptor — distinguishing it from peptide-based GLP-1 agonists such as semaglutide. It is currently in clinical development and has been evaluated in published Phase 2 and Phase 3 trial data examining its relationship to glycemic control and body-weight measures in study populations.

What is SLU-PP-332?

SLU-PP-332 is a synthetic small molecule studied as a pan-agonist across all three estrogen-related receptor (ERR) subtypes — ERRα, ERRβ, and ERRγ. Preclinical research describes it as an “exercise mimetic” candidate, based on reported effects on mitochondrial biogenesis and skeletal-muscle fiber-type composition in tested animal models.

Orforglipron — CAS Number 2212020-52-3
Orforglipron — Molecular Formula C48H48F2N10O5
Orforglipron — Molecular Weight ≈883.0 g/mol
SLU-PP-332 — CAS Number 303760-60-3
SLU-PP-332 — Molecular Formula C18H14N2O2
SLU-PP-332 — Molecular Weight 290.3 g/mol

Purity & Quality

First Class Science supplies this blend at research-grade (99%) purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch at https://firstclassscience.com/certificate-of-analysis/.

Storage: Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Important: This item is manufactured strictly for research purposes. It is not intended for human or veterinary use and is distributed solely for laboratory and scientific investigation.

Research Applications

Orforglipron — GLP-1 Receptor & Metabolic Research

Published clinical trial data has examined orforglipron’s effect on HbA1c and body-weight measures in study participants over multi-month treatment periods, reporting dose-dependent reductions across these measures relative to placebo arms. Because orforglipron is a non-peptide compound, published research has also examined its oral pharmacokinetic profile, distinguishing it from the injectable-peptide GLP-1 agonists more commonly represented in the literature.

SLU-PP-332 — Exercise-Mimetic & Mitochondrial Research

Preclinical research in cell and mouse models has examined SLU-PP-332’s effect on mitochondrial function and cellular respiration in skeletal-muscle cell lines, and on skeletal-muscle fiber-type composition and treadmill exercise-endurance measures in tested mice, reporting increases in oxidative (Type IIa) fiber proportion and endurance capacity in an ERRα-dependent manner in those models. This remains early-stage preclinical research that has not been evaluated in human trials.

Disclaimer: The research summarized above is drawn from third-party published studies conducted in animal, in vitro, or non-U.S. clinical contexts. It is provided for research and educational reference only and does not describe an intended use, effect, or benefit of this product for any person or animal.

⊗ ALL ITEMS ARE SOLD FOR RESEARCH USE ONLY. This category covers strictly in vitro laboratory testing and scientific experimentation. Content on this site is for education only and does not authorize human or animal use of any kind, which is prohibited by law. Only trained, licensed professionals should handle these materials. Nothing sold here qualifies as a drug, food, or cosmetic, and none of it may be labeled, advertised, or used as such.