Product Usage: For Research Use Only – Not for Human or Veterinary Use

This product is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is strictly intended for in vitro research by qualified professionals. Any use in humans or animals is strictly prohibited and may violate federal, state, or local laws, including the Federal Food, Drug, and Cosmetic Act. No therapeutic or diagnostic application is implied or permitted. The purchaser assumes all responsibility for compliance with applicable regulations.

Methylene Blue Capsules

Methylene Blue Capsules. Methylene blue is a well-characterized phenothiazine compound studied in published research for its interaction with mitochondrial electron-transport activity and, in early laboratory models, neurodegeneration-related pathways. Supplied at research-grade purity for laboratory use only.

$200.00

Methylene blue (methylthioninium chloride) is a synthetic phenothiazine dye first synthesized in the 19th century and among the most extensively characterized redox-active small molecules in the biochemical literature. It has a long history of laboratory and clinical use in areas such as methemoglobinemia and historically as an antimalarial, and remains a frequently studied compound in mitochondrial and neurodegeneration-focused research.

Product Details

  • What is Methylene Blue?
  • Chemical Identity
  • Research Applications

What is Methylene Blue?

Methylene blue is studied in laboratory research primarily for its role as an alternative electron carrier in the mitochondrial electron transport chain. Research describes methylene blue as able to accept electrons from NADH and donate them directly to cytochrome c, effectively bypassing Complex I and III activity in tested cell and tissue models — a property study authors have linked to observed changes in cellular oxygen consumption and ATP production in those models. At different concentrations, published research also describes both antioxidant and pro-oxidant behavior for the compound, a dose-dependent pattern noted repeatedly across the in vitro literature.

Chemical Identity

CAS Number 61-73-4
Molecular Formula C16H18ClN3S
Molecular Weight 319.85 g/mol

Purity & Quality

First Class Science supplies this compound at research-grade (99%) purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch at https://firstclassscience.com/certificate-of-analysis/.

Storage: Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Important: This item is manufactured strictly for research purposes. It is not intended for human or veterinary use and is distributed solely for laboratory and scientific investigation.

Research Applications

Mitochondrial & Cellular Metabolism Research

Published in vitro and animal-model research has examined methylene blue’s effect on mitochondrial respiration and cellular energy metabolism, reporting measurable changes in oxygen consumption and electron transport chain activity in tested cell lines and tissue preparations under specific dosing conditions.

Neurodegeneration-Related Models

A substantial body of preclinical research has examined methylene blue’s interaction with tau protein aggregation in cell and animal models relevant to tauopathies, along with its effects on markers of oxidative stress and mitochondrial function in neuronal cell models. Study authors describe these as laboratory findings requiring further mechanistic work rather than established clinical outcomes.

Historical Antimicrobial Research

Methylene blue has a long-documented research history as an antimalarial and antimicrobial redox agent, with in vitro and animal-model studies examining its activity against Plasmodium species and other pathogens dating back over a century.

Disclaimer: The research summarized above is drawn from third-party published studies conducted in animal, in vitro, or non-U.S. clinical contexts. It is provided for research and educational reference only and does not describe an intended use, effect, or benefit of this product for any person or animal.

⊗ ALL ITEMS ARE SOLD FOR RESEARCH USE ONLY. This category covers strictly in vitro laboratory testing and scientific experimentation. Content on this site is for education only and does not authorize human or animal use of any kind, which is prohibited by law. Only trained, licensed professionals should handle these materials. Nothing sold here qualifies as a drug, food, or cosmetic, and none of it may be labeled, advertised, or used as such.