Product Usage: For Research Use Only – Not for Human or Veterinary Use
This product is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is strictly intended for in vitro research by qualified professionals. Any use in humans or animals is strictly prohibited and may violate federal, state, or local laws, including the Federal Food, Drug, and Cosmetic Act. No therapeutic or diagnostic application is implied or permitted. The purchaser assumes all responsibility for compliance with applicable regulations.
5-Amino-1 MQ Capsules – 50mg
5-Amino-1MQ Capsules – 50mg. 5-Amino-1MQ is a small-molecule quinolinium compound studied in published preclinical research as a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Supplied at research-grade purity for laboratory use only.
$300.00
5-Amino-1MQ is a synthetic small molecule studied in preclinical research as a selective, substrate-competitive inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in the methylation and clearance of nicotinamide within cellular metabolic pathways.
Product Details
- What is 5-Amino-1MQ?
- Chemical Identity
- Research Applications
What is 5-Amino-1MQ?
NNMT, the enzyme 5-Amino-1MQ is studied for inhibiting, sits at the intersection of nicotinamide (a NAD+ precursor) metabolism and cellular methyl-donor (SAM/SAH) balance. Published preclinical research has examined how inhibiting NNMT activity with 5-Amino-1MQ affects markers of cellular metabolic rate, adipocyte biology, and methylation-dependent gene expression in tested cell and animal models. As a quaternary quinolinium compound, 5-Amino-1MQ is inherently a cationic species and is typically supplied and characterized as a salt (commonly the chloride or iodide form); the values below describe the cation.
Chemical Identity
| CAS Number | 42464-96-0 |
| Molecular Formula | C10H11N2+ (cation) |
| Molecular Weight | 159.2 g/mol (cation) |
Purity & Quality
First Class Science supplies this compound at research-grade (99%) purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch at https://firstclassscience.com/certificate-of-analysis/.
Storage: Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.
Important: This item is manufactured strictly for research purposes. It is not intended for human or veterinary use and is distributed solely for laboratory and scientific investigation.
Research Applications
NNMT Inhibition & Cellular Metabolism Research
Preclinical research in adipocyte and rodent models has examined NNMT inhibition via 5-Amino-1MQ in relation to markers of cellular energy expenditure and fat-cell metabolic activity, reporting changes in these measures in the tissue and animal models tested.
Methylation-Pathway Research
Because NNMT activity consumes methyl groups from the SAM/SAH cycle, published research has also examined 5-Amino-1MQ’s relevance to broader cellular methylation capacity and downstream gene-expression measures in tested cell models, an area study authors describe as still early in its preclinical characterization.
Disclaimer: The research summarized above is drawn from third-party published studies conducted in animal, in vitro, or non-U.S. clinical contexts. It is provided for research and educational reference only and does not describe an intended use, effect, or benefit of this product for any person or animal.
⊗ ALL ITEMS ARE SOLD FOR RESEARCH USE ONLY. This category covers strictly in vitro laboratory testing and scientific experimentation. Content on this site is for education only and does not authorize human or animal use of any kind, which is prohibited by law. Only trained, licensed professionals should handle these materials. Nothing sold here qualifies as a drug, food, or cosmetic, and none of it may be labeled, advertised, or used as such.