Product Usage: For Research Use Only – Not for Human or Veterinary Use
This product is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is strictly intended for in vitro research by qualified professionals. Any use in humans or animals is strictly prohibited and may violate federal, state, or local laws, including the Federal Food, Drug, and Cosmetic Act. No therapeutic or diagnostic application is implied or permitted. The purchaser assumes all responsibility for compliance with applicable regulations.
GLP-R
Lyophilized — must be reconstituted. GLP-R (Retatrutide) is a lab-developed tri-agonist peptide that research has examined for its interaction with GLP-1, GIP, and glucagon receptor signaling in laboratory and clinical study models. Supplied at research-grade purity for laboratory use only.
Price range: $125.00 through $700.00
GLP-R (research code for Retatrutide) is a synthetic peptide engineered as a triple agonist, designed to activate three distinct incretin-family receptors — GLP-1, GIP, and the glucagon receptor — simultaneously. The summary below reflects the published clinical-trial literature and is provided for research reference only.
What is GLP-R?
Where earlier incretin-based research compounds targeted one or two receptors, GLP-R was designed by researchers to engage all three of the GLP-1, GIP, and glucagon receptors within a single molecule, based on the hypothesis that combined agonism across these pathways could produce more pronounced downstream metabolic signaling than single- or dual-receptor agonism alone. Published Phase 2 clinical-trial research (results reported in the New England Journal of Medicine) examined this triple-agonist mechanism in a defined trial population over a 48-week study period, reporting body-weight-measure reductions considerably larger than those seen in earlier dual-agonist clinical research, at the highest tested dose. This research base is referenced here for research context only; the compound remains in clinical investigation and is not an approved medication.
Chemical Identity
| CAS Number | 2381089-83-2 |
| Molecular Formula | C221H342N46O68 |
| Molecular Weight | 4731.33 g/mol |
Purity & Quality
First Class Science supplies GLP-R at 99% purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch at https://firstclassscience.com/certificate-of-analysis/. Store lyophilised compound at −20°C for long-term stability. Refrigerate at 2–8°C after reconstitution and use within 4–6 weeks.
Important: This item is manufactured strictly for research purposes. It is not intended for human or veterinary use and is distributed solely for laboratory and scientific investigation.
Research Applications
Multi-Receptor Incretin Signaling Research
Published clinical and preclinical research has examined GLP-R/Retatrutide’s simultaneous engagement of GLP-1, GIP, and glucagon receptor pathways and the downstream association with appetite-signaling, energy-expenditure, and body-weight measures reported in tested clinical-trial populations.
Glycemic & Metabolic Marker Research
Clinical-trial research has also examined GLP-R/Retatrutide’s association with glycemic-control markers and lipid-panel measures in tested populations, an area of research that remains active as the compound continues through clinical investigation.
Disclaimer: The research summarized above is drawn from third-party published studies conducted in animal, in vitro, or non-U.S. clinical contexts. It is provided for research and educational reference only and does not describe an intended use, effect, or benefit of this product for any person or animal.
⊗ ALL ITEMS ARE SOLD FOR RESEARCH USE ONLY. This category covers strictly in vitro laboratory testing and scientific experimentation. Content on this site is for education only and does not authorize human or animal use of any kind, which is prohibited by law. Only trained, licensed professionals should handle these materials. Nothing sold here qualifies as a drug, food, or cosmetic, and none of it may be labeled, advertised, or used as such.