Product Usage: For Research Use Only – Not for Human or Veterinary Use
This product is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is strictly intended for in vitro research by qualified professionals. Any use in humans or animals is strictly prohibited and may violate federal, state, or local laws, including the Federal Food, Drug, and Cosmetic Act. No therapeutic or diagnostic application is implied or permitted. The purchaser assumes all responsibility for compliance with applicable regulations.
MK-677 Capsules
Capsule form — store in a cool, dry place. MK-677 (Ibutamoren) is an orally active ghrelin-receptor agonist that research has examined for its interaction with growth-hormone/IGF-1 axis signaling and sleep-architecture measures in laboratory and clinical study models. Supplied at research-grade purity for laboratory use only.
$250.00
MK-677 (Ibutamoren) is a synthetic, orally active, non-peptide compound developed to act as a selective agonist of the ghrelin receptor (GHS-R1a), studied for its downstream stimulation of growth-hormone (GH) and insulin-like growth factor 1 (IGF-1) secretion. The summary below reflects the published clinical and preclinical literature and is provided for research reference only.
What is MK-677?
Research has examined MK-677’s binding to the ghrelin receptor in the pituitary and hypothalamus, reporting that this interaction stimulates pulsatile GH release and sustained elevation of circulating IGF-1 in tested clinical and preclinical models, distinguishing it from injectable GH-releasing peptides due to its oral route of administration and reported longer duration of action in the models studied.
Chemical Identity
| CAS Number | 159634-47-6 |
| Molecular Formula | C27H36N4O5S |
| Molecular Weight | 528.66 g/mol |
Purity & Quality
First Class Science supplies MK-677 Capsules at 99% purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch at https://firstclassscience.com/certificate-of-analysis/. Store in a cool, dry place away from direct sunlight and moisture; keep out of reach of children.
Important: This item is manufactured strictly for research purposes. It is not intended for human or veterinary use and is distributed solely for laboratory and scientific investigation.
Research Applications
Growth-Hormone / IGF-1 Axis Research
Published clinical research has examined MK-677’s association with sustained elevations in GH pulse amplitude and circulating IGF-1 concentrations across tested human study populations, including research in older adults and in defined patient populations studied for GH-axis-related measures.
Sleep-Architecture Research
Clinical research has examined MK-677’s association with sleep-quality measures, including reported increases in REM and stage-4 (slow-wave) sleep duration in tested study populations, an area of research distinct from its GH-axis findings.
Body-Composition & Muscle-Wasting Research
Research has examined MK-677’s association with lean-body-mass and appetite-related measures in tested clinical populations, including studies in populations characterized by muscle-wasting-related conditions.
Disclaimer: The research summarized above is drawn from third-party published studies conducted in animal, in vitro, or non-U.S. clinical contexts. It is provided for research and educational reference only and does not describe an intended use, effect, or benefit of this product for any person or animal.
⊗ ALL ITEMS ARE SOLD FOR RESEARCH USE ONLY. This category covers strictly in vitro laboratory testing and scientific experimentation. Content on this site is for education only and does not authorize human or animal use of any kind, which is prohibited by law. Only trained, licensed professionals should handle these materials. Nothing sold here qualifies as a drug, food, or cosmetic, and none of it may be labeled, advertised, or used as such.