Product Usage: For Research Use Only – Not for Human or Veterinary Use
This product is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is strictly intended for in vitro research by qualified professionals. Any use in humans or animals is strictly prohibited and may violate federal, state, or local laws, including the Federal Food, Drug, and Cosmetic Act. No therapeutic or diagnostic application is implied or permitted. The purchaser assumes all responsibility for compliance with applicable regulations.
GLP-S
Lyophilized peptide, for reconstitution per COA instructions. GLP-S (semaglutide) is a GLP-1 receptor agonist studied in extensive published clinical and preclinical research for glycemic and body-weight measures. Supplied at research-grade purity for laboratory use only.
Price range: $75.00 through $325.00
GLP-S is First Class Science’s research-grade preparation of semaglutide, a synthetic analog of human glucagon-like peptide-1 (GLP-1) engineered for extended receptor engagement. Semaglutide is among the most extensively studied GLP-1 receptor agonists in the published clinical literature, and the summary below reflects that research base for reference only.
What is GLP-S?
Semaglutide is modified from native GLP-1 with amino-acid substitutions and a fatty-diacid side chain that promotes albumin binding, a design reported to slow renal clearance and extend the peptide’s half-life to support once-weekly dosing regimens studied in clinical trials. Researchers have examined semaglutide’s binding to the GLP-1 receptor and downstream signaling effects on insulin secretion, gastric emptying, and central appetite-regulation pathways in cell, animal, and human study models.
Randomized controlled trials (including the STEP program, published in journals such as the New England Journal of Medicine) have examined semaglutide’s association with body-weight and glycemic-control measures in defined trial populations. This clinical research base supported approval of semaglutide-containing products (marketed as Ozempic and Wegovy) for specific indications — uses distinct from, and not implied by, the research-use-only status of this product.
Chemical Identity
| CAS Number | 910463-68-2 |
| Molecular Formula | C187H291N45O59 |
| Molecular Weight | ~4113.6 g/mol |
Purity & Quality
First Class Science supplies GLP-S at 99% purity, verified by independent third-party HPLC testing and mass spectrometry. A Certificate of Analysis is available for every batch at https://firstclassscience.com/certificate-of-analysis/. Store lyophilised compound at −20°C for long-term stability; refrigerate at 2–8°C after reconstitution and use within 4–6 weeks.
Important: This item is manufactured strictly for research purposes. It is not intended for human or veterinary use and is distributed solely for laboratory and scientific investigation.
Research Applications
GLP-1 Receptor Pathway & Glycemic Research
Randomized clinical trials (Wilding et al., New England Journal of Medicine, 2021, among others in the STEP trial program) examined semaglutide’s association with body-weight change and glycemic measures relative to placebo in defined adult trial populations, reporting effects study authors attributed to GLP-1 receptor-mediated appetite and insulin-signaling pathways.
Central Appetite-Regulation Research
Preclinical research in animal models has examined semaglutide’s engagement of GLP-1 receptors in hypothalamic and brainstem appetite-regulation circuits, proposed by study authors as a contributing mechanism to the food-intake measures reported in downstream clinical research.
Cardiometabolic Signaling Research
Additional published research has examined GLP-1 receptor agonism in relation to cardiovascular and metabolic biomarkers in clinical trial populations, an active area of ongoing published investigation.
Disclaimer: The research summarized above is drawn from third-party published studies conducted in animal, in vitro, or non-U.S. clinical contexts. It is provided for research and educational reference only and does not describe an intended use, effect, or benefit of this product for any person or animal.
⊗ ALL ITEMS ARE SOLD FOR RESEARCH USE ONLY. This category covers strictly in vitro laboratory testing and scientific experimentation. Content on this site is for education only and does not authorize human or animal use of any kind, which is prohibited by law. Only trained, licensed professionals should handle these materials. Nothing sold here qualifies as a drug, food, or cosmetic, and none of it may be labeled, advertised, or used as such.